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One side effect is SUDDEN DEATH!

July 3rd, 2009

Jim


“You can’t do that,” I said, “You will kill this guy.”  I had waited for a good five minutes for this nurse in Omaha, Nebraska.  She sounded like your mother’s Aunt Eda.  Slow talking.  Slow responding. 
She giggled nicely though.  I was expecting a “Whatever!”
“Mister Frasier knows better than to use Nitroglycerin on the [...]

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FDA Panel: Ban APAP and Hydrocodone

July 1st, 2009

Jim


This is a game changer.  If they ban the hydrocodone/APAP combinations, that will be the end of Schedule III hydrocodone.  JP thinks this would be a good thing.  If MDs want to run “Prescription Mills” I want their DEA recorded with each Rx.   Here is the whole magilla if you want to read it.
FDA urged to [...]

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“Do you want to help her, Maam?”

July 1st, 2009

Jim


I was up to my ass in alligators when a heavy set twenty-something woman asked for my help.  She was pleasant and waited her turn.  I was happy to help her, if I could.
I had a hard time not laughing because she sort of hopped as she walked.  Her problem was a broken toe, the [...]

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I Noticed It Again Last Friday.

June 30th, 2009

DrugMonkey, Master of Pharmacy


My Fridays have fallen into a pattern, as that is the day of the week when I put in my 12 hour shift in the happy pill room, and after a 12 hour shift, I’m not interested in looking at a wine list, or hearing about how the carmalization of the sauce on some piece of meat the food section of The New York Times has elevated to a status symbol will mix perfectly with the organic fruit dessert flown in this morning from Peru. I just want to get some calories in my stomach and get the hell home. That leaves me one and just one choice in the den of affluenza where I sling the pills these days. Subway. I miss my days in the ghetto where I had a wide variety of empty calorie houses from which to choose and the people were far more interesting, but Subway it was again last week whether I liked it or not. The home of Jared has become part of my Friday night ritual by default.

As had the family on the other side of the room. Father, mother, and four little ones all munching away on subs or chips or cookies or whatever else the Subway peddles these days. One little girl was playing away with some sort of toy promotion for the Land of The Lost movie, which I’ve heard is terrible. I figured the little girl would never see it though, as the family didn’t look like the type that spent much time at the theatre. From the enthusiasm of the little ones and the fact that I’ve seen them there every Friday night for a couple months now, I’m pretty comfortable in saying that Friday night at Subway was the big family outing for the week.
The same way a trip to McDonald’s was a big outing for the little drugmonkey’s family.
The short sleeved plaid workshirt the father wore looked awfully familiar.
I was looking through a mirror into my childhood, because you see, before the agents of capital started luring the hablaers of español northward to provide cheap labor, they were luring the hillbillies out of the holler to do the same.

…..To the jobs that lay waiting in those cities’ factories
They learned
readin‘, rightin‘, roads to the north
To the luxury and comfort a coal line can’t afford
They thought
readin‘, rightin‘, route 23
Would take them to the good life that they had never seen
They didn’t know that old highway
Could lead them to a world of misery

Dwight Yoakum wasn’t singing about today’s immigrants, although the story sounds kinda familiar, doesn’t it? I know exactly where route 23 is. It leads up from the hollers of Kentucky to the spirit crushing jobs of the North. I’ve driven on it many a time. Up from the land of poverty to the promise of work it goes.
Up from the land of poverty to the promise of work. Sound familiar? Does it? Because honest to God it seems like sometimes I am the only person on earth who can make a connection between yesterday’s Tom Joads and today’s Felipe Hernandezes. The only one who sees that Sabado Grande looks an awful lot like the Hee Haw we used to watch on Saturday nights. I used to work in the ghetto, and although I couldn’t understand a word they were saying, a lot of my customers in the ghetto reminded me an awful lot of the hillbillies back home.
But it feels like I am the only person who can see it. Because the grandchildren of Tom Joad can’t get past the fact that the people who took their place on the economic ladder came north hablaing español. So the grandchildren of Tom Joad are duped into thinking they have far more in common with the white people on Wall Street than they do with the people who currently do the work their grandparents did. The work that laid the foundation for the grandchildren of Tom Joad to be elevated into the upper middle class. Where they were taken advantage of by the Barons of Wall Street they thought they had so much in common with. Checked your 401k balance lately?
It’s kinda like the way Tom Joad was taken advantage of by the Barons of Agriculture.
I watched as the little girl in Subway happily showed off her dinosaur cup to her brothers, and I could almost hear the voice of soul rotting affluence on the other side of the mall angrily sending back his meat of the moment. I could imagine the meat of the moment wasn’t cooked the way the New York Times said it should be cooked, and the grandchildren of Tom Joad are all about showing their status, which is defined by whatever the New York Times says it should be. You know it happened.
And I know I’ll look forward to heading back to Subway this Friday.
I think that little girl’s gonna turn out all right.
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Pharmacy Junk Mail In More Than One Sense Of The Word. Look How Much Better Glumetza® Is Than Regular Metformin

June 29th, 2009

DrugMonkey, Master of Pharmacy


I mean seriously, just look at this graph. You’d have to be stupid not to realize how much better Glumetza™ is.

You probably don’t even need or want to be told at this point that Glumetza™ is simply an extended-release version of the diabetes medicine metformin, which also goes by the brand name Glucophage. It doesn’t matter. Look at the graph. Glumetza is way better. That’s why the Glumetza® bar is orange and the numbers at the top are way bigger. Because Glumetza® is obviously way better.

Santaris Inc. and Depomed, the makers of Glumetza® would like you to stop reading now. They would also like you to not notice or pay attention to the top of the graph, where it clearly says that they used a daily dose 33% higher to get that pretty orange bar.
Or at the very least, they would not like you to think about how maybe it’s not all that surprising that when you give a dose of a drug that is higher, it might be more effective.
Here are some other tidbits from the text of the same Glumetza® ad:
Unlike generic immediate-release metformins, Glumetza® uses advanced polymer technology, which provides controlled release of metformin targeting the upper GI system. As a result, more drug enters the bloodstream and less unabsorbed drug remains in the lower GI tract. This may help reduce GI adverse events.

I see. Well I think Glumetza ® may make your penis fall off. And I have provided as much proof for this claim as Santaris Inc. and Depomed have for theirs.
In the clinical trial above, Glumetza® was well tolerated at higher doses. The overall incidence of drug related AEs (adverse effects) was 35% for Glucophage 1500mg/day BID and 33% for Glumetza® dosed up to 2000mg QD.

Sweet. A 2% reduction of the chance of any side effects is totally worth paying $190 extra dollars a month for. Which is what Glumetza® will set you back as opposed to the dirt cheap metformin.
The regular metformin’s bar in the graph isn’t orange though.
Less than 1% Glumetza® patients discontinued treatment due to GI AEs in the first week of the study, when the assigned dose was 1000mg/day.

Except that pretty orange bar was for a dose of 2000mg/day. Santaris Inc. and Depomed don’t seem to want to mention how many people discontinued treatment at this dose. So I’ll just assume it’s somewhere around 95%.
Sigh. You know, the fact that a drug manufacturer massages some numbers around isn’t what bothers me here. Drug manufacturers have massaged numbers around at least since I was a drunken frat boy. They used to be far sneakier about it though. Now it’s like they don’t even care, and I miss being respected enough that they would at least try to spray some Lysol on their bullshit. These days it’s like Big Pharma is giving bulls a special diet to make their shit extra stinky or something.
And evidently extra stinky bullshit works on someone out there. Because I filled a prescription for Glumetza® yesterday. That’s what bothers me.
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One pharmacy to rule them all…

June 25th, 2009

theangrypharmacist


Going along with my previous (and popular) socialized medicine post, I have a solution from the pharmacy aspect that I thought of while reading some responses to it.
You see, we shouldn’t have the folks like Walgreens, Rite-Aid (if they are still around), CVS, and the hundreds of independents profiting off of the pain and suffering [...]

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A Little Bit Crazy?

June 24th, 2009

Jim


A Bad Hair Crazy Day
Crazy does not mean anti-social.  Crazy does not necessarily mean unkempt, unsanitary, offensive or mean-spirited.  Crazy is not silly, laughable or entertainment.  Crazy is definitely not stupid. 
 
Ever since Ronald Reagan said, “We will no longer warehouse our mentally ill”, the pharmacy is the place where they get the gear needed [...]

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BarryCare

June 24th, 2009

Pharmacy God


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Drive Thru Douchette

June 22nd, 2009

Filet-o-bitch RPh


Dear drive thru douchette,

If you don’t know how to fucking use a drive thru, don’t use it! Why do we need a 5 minute banter about why you can’t see me and how are you to get a “freaking” prescription filled if you can’t see where I am? Did it not occur to your small brain that perhaps I am using a phone from a remote location to ask you if you want to pick up a rx or drop off a rx TO SAVE SOME FUCKING TIME? Do you see the Mickey D’s teenage employee when they take your order at the big window b/c God knows you go their tri daily! See the big drawer in front of your dumb ass that is too lazy to walk into the store? By some miracle, that actually opens so that you may place your prescription in it. Magical fairies then fly over to sweep the rx from the drawer and little elves run around with their heads cut off to fill your vicodin stat. Whooooo hooooo! Why bitch at me and repeat to yourself “I can’t see you!” Who cares! I don’t want to see you either!

Love,
Filet

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85% Of People Say The Health Care Systen In This Country Needs To Be Destroyed. Today We Let The Other 15% Have A Say.

June 21st, 2009

DrugMonkey, Master of Pharmacy


That 85% number comes from a poll published in Saturday’s New York Times:

85 percent of respondents said the health care system needed to be fundamentally changed or completely rebuilt

Fuck yeah. Now we’re talking. We must be about ready to steamroll the last few remaining pathetic bastards defending the status quo and finally make some progress towards joining the rest of the civilized world in ensuring our citizens don’t have to worry about losing their house to foreclosure if they have the rudeness to become ill. Right?

Right?

Not necessarily. Would you have guessed that only 15% of people support the present system? I’m betting not. The right wing is very skillful at the construction of Potemkin villages to make it appear they are far more numerous than they really are. You can do that kind of thing when you control Fox News, The Murdoch newspaper publishing empire, and pretty much the entirety of the AM radio dial. It also helps to shout a lot. There is another level to right wing media though. Publications like the National Review, founded by William F. Buckley to be the flagship of intellectual conservatism. In other words, to serve the people who actually benefit from right wing ideology, as opposed to the white trash mindset that Bill O’Reilly is paid big bucks to whip into a frenzy to think they are better off shunning those dreaded liberals and their sense of fairness.

The National Review recently took its best shot at defending the system that is bankrupting us both individually and as a nation, which isn’t really surprising, since our bankruptcy is by and large their reader’s profit. Gather round folks, and get ready to listen to the extinction cry of those who build their mansions with our blood money.

I wrote back in December of 2007 that our heathcare *cough* system produces fewer doctors, fewer nurses, and fewer hospital beds per capita than the average country in the Organization for Economic Co-operation and Development, which any human would interpret as a sign of trouble. Remember though, that right wing conservatives, while having opposable thumbs, rudimentary tool-using and speech capability, and binocular vision, are not fully human:

One gets a better measure of how much countries spend by looking at the real resources used; and by that measure, the U.S. system is pretty good. For example, we use fewer doctors than the average developed country to produce the same or better outcomes. We also use fewer nurses and fewer hospital beds, make fewer physician visits, and spend fewer days in the hospital.

So, next time you go to the ER and get yourself stacked up in the hall waiting to see a doctor for 6 hours, the next time you’re lying in your own urine in a hospital bed desperately pressing a call button that the nurse handling a crisis at the other end of the hall can’t hear, just remember, it’s a sign that the U.S. system is pretty good! I bet the editor of The National Review checks to see which hospital in his area has the fewest doctors and nurses per patient whenever he needs care. I bet he also picks an insurance plan for himself that boots him out of the hospital as soon as possible, because hitting the street in a post-op state where you can barely stand up would definitely be sign you are in a health care system that is pretty good.

By the way, many of you may have shot a beverage out of your nose when you saw the National Review assert the U.S. system produces “the same or better outcomes,” as that flies in the face of every single fucking piece of evidence on the planet. We’ll get to that, but first:

Other countries are far more aggressive than we are at disguising and shifting costs — for example, by using the power of government purchase to artificially suppress the incomes of doctors, nurses, and hospital personnel. This makes their aggregate outlays look smaller when all that has really happened is that part of the cost has been shifted from one group (patients and taxpayers) to another (health-care providers). This is equivalent to taxing doctors, nurses, or some other group so that others may pay less for their care.

Soooooo…..other countries have their health care workers in oppressive chains, paying them slave wages so other people can get recreational coronary bypasses. Except….um…..as we just saw, the U.S. has fewer healthcare workers per capita than other countries in our peer group. So….when you pay people less to do something, you get more people who are willing to do it?
My God, The National Review just turned the basic tenet of Economics 101 on its head. I bet they’ll win a goddamn Nobel Prize or something. Or else they’re just full of shit.
The National Review also comes up with a little outside the box thinking to explain why health outcomes in the U.S. just never seem to measure up to the rest of the industrialized world:

Critics point to the fact that U.S. life expectancy is in the middle of the pack among developed countries, and that our infant-mortality rate is among the highest. But are these the right measures? Within the U.S., life expectancy at birth varies greatly between racial and ethnic groups, from state to state, and across counties….

All too often, the heterogeneous population of the United States is compared with the homogeneous populations of European countries. A state such as Utah compares favorably with almost any developed country. Texas, with its high minority population, tends to compare unfavorably. But these outcomes have almost nothing to do with the doctors and hospitals in the two states.

Uh-huh. Now those of you out there who aren’t white won’t need me to translate that for you. The honkies amongst you though, may not be used to the thin veneer of subtlety applied here to what they are actually saying, which is:

All those brown and black people shouldn’t really count. Because they’re not real Americans.
Which is bad enough. The buttwipe who wrote this article though, a near-human by the name of John C. Goodman, also happens to have his facts wrong. Let’s take a look at the “homogeneous populations” of a few European countries:
17% of the population of France isn’t white.
Germany? 18 percent.
Netherlands. 20 percent. That’s one in five.
All those countries beat the living piss out of the United States, whose minority population is 26%, in almost any way you wanna measure their people’s health. John C. Goodman evidently feels that somewhere between a minority population of 20 to 26 percent, there is a point that will trigger the collapse of a country’s health care system.
Or he happily wallows in the mud if ignorance.
Or he’s just a racist.
So there you are my friends. Everything is just fine. We really need fewer doctors and nurses, and if we wanted more we could always just pay them starvation wages like the Europeans do in some fantasy world. And people who aren’t white really don’t need medical care anyway. That’s the position of the publication that considers itself the pillar of serious conservative thought in this country.
That’s seriously the best they can do. If this fight is fought on just the facts, we will win in a landslide.
Let’s make sure the fight is fought on just the facts.
Thanks to some asshole who can’t write or form a coherent argument named Chip for sending that article my way, even though he was just trying to be a dick.
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